Medications that Interact with CBD

UPDATED ON DECEMBER 20, 2018

If you’re planning on using CBD, speak to your doctor about possible interactions it can have with other drugs that you’re taking. CBD can interact with any drug metabolized by cytochrome P450 enzymes (a family of liver enzymes), so you definitely should talk to your doctor if you are thinking about taking CBD and you’re taking any pharmaceuticals. When you take CBD, the liver stops metabolizing other drugs which use the same enzyme, so the other drugs not being metabolized by the liver will stay in your system longer. These drugs (listed by CBD Oil review) may include:

  • Steroids
  • HMG CoA reductase inhibitors
  • Calcium channel blockers
  • Antihistamines
  • Prokinetics
  • HIV antivirals
  • Immune modulators
  • Benzodiazepines
  • Antiarrythmics
  • Antibiotics
  • Anesthetics
  • Antipsychotics
  • Antidepressants
  • Anti-epileptics
  • Beta blockers
  • PPIs
  • NSAIDs
  • Angiotension II blockers
  • Oral hypoglycemic agents
  • Sulfonylureas